Project Mercury
| Flight | Prime | Backup |
|---|---|---|
| Mercury-Redstone III | Al Shepard | John Glenn |
| Mercury-Redstone IV | Gus Grissom | John Glenn |
| Mercury-Atlas VI | John Glenn | Scott Carpenter |
| Mercury-Atlas VII | Scott Carpenter | Wally Schirra |
| Mercury Atlas VIII | Wally Schirra | Gordo Cooper |
| Mercury Atlas IX | Gordo Cooper | Al Shepard |
Project Gemini
| Flight | Prime | Backup | ||
|---|---|---|---|---|
| Commander | Pilot | Commander | Pilot | |
| Gemini 3 | Gus Grissom | John Young | Wally Schirra | Tom Stafford |
| Gemini IV | Jim Mcdivitt | Ed White | Frank Borman | Jim Lovell |
| Gemini V | Gordo Cooper | Pete Conrad | Neil Armstrong | Elliot See |
| Gemini VII | Frank Borman | Jim Lovell | Ed White | Mike Collins |
| Gemini VI-A | Wally Schirrah | Tom Stafford | Gus Grisson | John Young |
| Gemini VIII | Neil Armstrong | Dave Scott | Pete Conrad | Dick Gordon |
| Gemini IX-A1 | Tom Stafford | Gene Cernan | Jim Lovell | Buzz Aldrin |
| Gemini X | John Young | Mike Collins | Al Bean | C. C. Williams |
| Gemini XI | Pete Conrad | Dick Gordon | Neil Armstrong | Bill Anders |
| Gemini XII | Jim Lovell | Buzz Aldrin | Gordo Cooper | Gene Cernan |
Project Apollo
| Flight | Prime | Backup | ||||
|---|---|---|---|---|---|---|
| Commander | CMP | LMP | Commander | CMP | LMP | |
| Apollo 7 | Wally Schirra | Donn Eisele | Walt Cunningham | Tom Stafford | John Young | Gene Cernan |
| Apollo 8 | Frank Borman | Jim Lovell | Bill Anders | Neil Amstrong | Buzz Aldrin | Fred Haise |
| Apollo 9 | Jim McDivitt | Dave Scott | Rusty Schweickart | Pete Conrad | Dick Gordon | Al Bean |
| Apollo 10 | Tom Stafford | John Young | Gene Cernan | Gordo Cooper | Donn Eisle | Ed Mitchell |
| Apollo 11 | Neil Armstrong | Mike Collins | Buzz Aldrin | Jim Lovell | Bill Anders | Fred Haise |
| Apollo 12 | Pete Conrad | Dick Gordon | Al Bean | Dave Scott | Al Worden | Jim Irwin |
| Apollo 13 | Jim Lovell | Jack Swigert | Fred Haise | John Young | Jack Swigert | Charlie Duke |
| Apollo 14 | Al Shepard | Stu Roosa | Ed Mitchell | Gene Cernan | Ron Evans | Joe Engle |
| Apollo 15 | Dave Scott | Al Worden | Jim Irwin | Dick Gordon | Vance Brand | Jack Schmitt |
| Apollo 16 | John Young | Ken Mattingly | Charlie Duke | Fred Haise | Stu Roosa | Ed Mitchell |
| Apollo 17 | Gene Cernan | Ron Evans | Jack Schmitt | John Young | Stu Roosa | Charlie Duke |
Skylab
| Flight | Prime | Backup | ||||
|---|---|---|---|---|---|---|
| Commander | Science Pilot | Pilot | Commander | Science Pilot | Pilot | |
| Skylab 2 | Pete Conrad | Joe Kerwin | Paul Weitz | Rusty Schweickart | Story Musgrave | Bruce McCandless |
| Skylab 3 | Al Bean | Owen Garriott | Jack Lousma | Vance Brand | Bill Lenoir | Don Lind |
| Skylab 4 | Jerry Carr | Ed Gibson | Bill Pogue | Vance Brand | Bill Lenoir | Don Lind |
Apollo-Soyuz
| Prime | Backup | ||||
|---|---|---|---|---|---|
| Commander | CMP | Docking MP | Commander | CMP | Docking MP |
| Tom Stafford | Vance Brand | Deke Slayton | Al Bean | Ron Evans | Jack Lousma |